Studies

Stroboscopic Visual Training: a Pilot Study with Three Elite Youth Football Goalkeepers

This pilot study delves into the effectiveness of Stroboscopic Visual Training (SVT) in enhancing visual and perceptual performance among elite youth football goalkeepers. SVT, involving intermittent vision conditions during activities, has exhibited positive outcomes in visual memory, anticipation, and dynamic acuity. After the 7 week trial, participants reported improved judgment, focus, and concentration.

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Affective and Cognitive Reactions to Subliminal Flicker From Fluorescent Lighting

This study challenges the traditional notion of subliminal perception by investigating the effects of subliminal flicker from fluorescent lighting on affect and cognitive performance. The research hypothesized that low-frequency flickering lighting would evoke stronger changes in affective states and impair cognitive performance compared to high-frequency lighting. Surprisingly, participants reported higher frequency lighting as more pleasant, correlating with enhanced problem-solving performance. The study suggests that sensory processing, undetectable consciously, can still impact conscious emotional states, indicating a role of affect in subliminal perception.

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Gamma Frequency Sensory Stimulation Prevents Brain Atrophy, Improves Sleep and Memory in Probable Mild Alzheimer’s Patients

In a groundbreaking study, non-invasive gamma frequency light and sound stimulation at 40Hz, previously effective in reducing Alzheimer's disease (AD) pathology in mouse models, was tested in a placebo-controlled trial involving 15 volunteers with probable mild AD. Administered daily for 3 months, the novel light and sound device induced safe and effective 40Hz entrainment, preventing hippocampal atrophy and ventricular enlargement associated with AD-related degeneration. Compliance was high, and improvements were observed in circadian rhythmicity and face-name association delayed recall test accuracy. These findings suggest that gamma frequency sensory stimulation holds promise as a safe and potentially disease-modifying therapeutic for Alzheimer's dementia.

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Overture Study

The OVERTURE Phase 2 trial demonstrated promising outcomes in treating mild- and moderate-stage Alzheimer's patients with non-invasive gamma therapy. Patients receiving the therapy exhibited significant cognitive preservation, with a 76% reduction in cognitive decline, as measured by MMSE score. Additionally, there was a substantial 77% slowing of decline in daily function (ADCS-ADL total score) and a notable 69% reduction in brain volume loss measured by MRI, suggesting potential benefits for both functional and structural aspects of Alzheimer's progression. The trial reported no adverse events, underlining the treatment's safety, and 85% adherence highlighted strong participant commitment to the therapy.

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Preliminary Assessment on the Effectiveness of the Luminette® in Adolescents With Adelayed Sleep Phase Syndrome (DSPS)

In a pilot study involving 10 adolescents (average age 16.3) with Delayed Sleep Phase Syndrome (DSPS), the effectiveness of a light therapy device was assessed using a randomized single-blind placebo-controlled design. Participants using the device showed significant improvements compared to the placebo group in terms of sleep onset delay, sleep quality, and daytime sleepiness, as measured by the Teen Sleep Diary and the Pediatric Daytime Sleepiness Scale.

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Impact of the Use of Luminette® on Well-Being at Work in a Radiotherapy Department

A randomized cross-over study was conducted in a radiotherapy department without access to natural light to analyze the impact of light exposure on wellbeing at work. The study involved alternating periods of four weeks using a light therapy product and four weeks without. Participants (n=25, average age=36.5) reported several benefits after one month of use, including improved diurnal slumber, general health perception, physical functioning, reduced pains, and diminished role limitations due to emotional problems. Notably, some benefits persisted even a month after discontinuing light therapy.

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